Pattern Recognition of Glycyrrhiza uralensis Metabonomics on Rats with MixOmics Package of R Software

摘要：

The most widely-used function of Glycyrrhiza uralensis in clinical is regulating property of other drugs, but its mechanism is not explicit. In order to reveal its mechanism, we carried out metabonomics study.The exported LC/MS data were processed by mixOmics package with R.PCA function-including PCA, iPCA and sPCA, PLSDA including valid, and VIP were used to perform pattern recognition.Ability of different functions was evaluated.The results showed PLSDA has powerful discriminative ability of pattern recognition.The mixOmics package is a very useful tool for pattern recognition in metabonomics study.

关键词： Pattern recognition Glycyrrhiza uralensis mixOmics R

作者: Wen Rui Yifan Feng Miaomiao Jiang Liang Wang Xiaomei Zhang Zhongfeng Shi

作者单位: Center Laboratory,Guangdong Pharmaceutical University,510006,Guangzhou,China

会议类型: 国际会议

会议名称: International Conference on Advances in Engineering 2011(2011年工程研究进展国际学术会议 ICAE2011)

会议地点: 南京

会议语种:英文

页码: 510-514

在线出版日期: 2011-12-17（万方平台首次上网日期，不代表论文的发表时间）