THE LATEST DEVELOPMENTS ON SINGLE DROPLET TECHNIQUE TO OBSERVE PARTICLE FORMATION AND TO ENGINEER PARTICLE QUALITY

摘要：

Spray drying is a common manufacturing technique in food and pharmaceutical industries; advances in drying kinetics studies have improved the product quality and minimized over-processing.Single droplet drying is a conventional method for studying the drying kinetics and droplet morphological changes under conditions analogous to spray drying.Further particle quality engineering, however, requires understandings on both the particle formation mechanisms and the effect of drying conditions on particle properties.Latest development on single droplet technique enables the evaluation of these two aspects by incorporating the dissolution test.By attaching a solvent droplet to the single dried particle, some of the particle functionalities can be examined, including wettability, dissolution rate and material dissociation behaviour.This method can be further extended to combine with post-drying analysis as well as in situ analysis of particle evolution, consequently providing a powerful tool for unveiling mechanisms of some fundamental phenomena during drying.

关键词： Single droplet drying glass filament approach particle engineering drying kinetics dissolution

作者: Nan Fu Meng Wai Woo Xiao Dong Chen

作者单位: Department of Chemical Engineering,Monash University,Clayton campus,Wellington Rd,Clayton,Victoria 3 Department of Chemical Engineering,Monash University,Clayton campus,Wellington Rd,Clayton,Victoria 3

会议类型: 国际会议

会议名称: The 7th Asia-Pacific Drying Conference(第七届亚太地区干燥会议 ADC2011)

会议地点: 天津

会议语种:英文

页码: 1-8

在线出版日期: 2011-09-18（万方平台首次上网日期，不代表论文的发表时间）