Partitioning Behavior of Penicillin G in Aqueous Two Phase System Based on Ionic Liquids

摘要：

An aqueous two-phase system (ATPS) was presented with hydrophilic ionic liquid l-Butyl-3-methylimid- azolium tetrafluoroborate(BmimBF4) and salts for the extraction of penicillin G in this paper. The phase-forming abilities of different salts were investigated to choose a suitable salt.The partitioning behavior of penicillin G in the ATPS was investigated.Concentrations of (NR4)2SO4, penicillin G, and BmimBF4 were evaluated to determine their effects on the extraction yield of penicillin G. It was found that extraction yield strongly depended on the concentration of BmimBF4, penicillin and (NH4)2SO4. A high extraction yield around 93％ was achieved with the following parameters: (NH4)2SO4 20％ (wt％), penicillin 40000-45000 U/mL, (Bmim)BF420％ (wt％).

关键词： ionic liquid extraction aqueous two-phase system penicillin

作者: Bin Jiang Zhibiao Feng Chunhong Liu Yingcao Xu Dongmei Li Guo ji

作者单位: Department of Applied Chemistry, College of science,Northeast Agricultural University,Harbin, China

会议类型: 国际会议

会议名称: The 2012 International Conference of Agricultural Engineering and Food Engineering(2012年国际农业工程与食品工程学术会议 ICAE 2012)

会议地点: 哈尔滨

会议语种:英文

页码: 851-853

在线出版日期: 2012-06-16（万方平台首次上网日期，不代表论文的发表时间）