Studies on the Action Mechanism for Cholesterol- lowering of Lactobacillus which yields Bile Salt Hydrolase from Kefir Graifts
Cholesterol-lowering strains were obtained by high throughput screening technology and orthophthalaldehyde method. We used oxford cup method to screen again to obtain strains of high yield bile salt hydrolase and illuminate action mechanism of Lactobacillus reducing cholesterol. Screened six strains had the ability of high yield bile salt hydrolase and good ferment ability. The results of identifying bacteria species: strain KTx、KL1、J1 were Lactobacillus casei, strain Tx was Streptococcus thermophUus, strain KS4、P1 were Lactococcus lactis subsp.lactis, where the last two bacteria were strain of high yield bile salt hydrolase to be few known in literature. This work showed that dissociation bile salts and cholesterol conjuncted sediments by bile salt hydrolase decomposing conjugated bile salts.
kefir grains Lactobacillus bile salt hydrolase action mechanism
Hui Liu Yuanhong Xie Tao Han Hongxing Zhang
College of Food Science, Beijing University of Agriculture Beijing, China Beijing Key Laboratory of Agricultural Product Detection and Control of Spoilage Organisms and Pesti
国际会议
哈尔滨
英文
867-870
2012-06-16(万方平台首次上网日期,不代表论文的发表时间)