SELECTIVE PRESSURE ANALYSIS OF LEPTOSPIRA_INTERROGANS_SEROVA_LAI BASED ON DIFFERENTIAL EQUATION

摘要：

In order to acquire selective pressure analysis of Leptospira_Interrogans_ Serova_Lai using the concept of gene duplication, synonymous and nonsynonymous substitution based on differential equation is used to analysis the selective pressure in this paper.By introducing the gene duplication, the model can rationally acquire the selective pressure of the duplicate genes, comparing the rates of synonymous and non-synonymous.The result shows that early in their history for Leptospirainterrogansserovar_Lai, many gene duplicates experience a phase of relaxed purifying selection, subsequently selection constraint gradually increases and eventually tended to the stability.

关键词： Leptospira_interrogans_serova_Lai Differential equation Gene duplication Non synonymous substitution Synonymous substitution

作者: XIAOFENG WANG BAOGUANG SUN

作者单位: College of Mathematical and Physical Sciences,Chongqing University of Science and Technology,Chongqing,China

会议类型: 国际会议

会议名称: 2011 3rd International Conference on Computer Technology and Development(2011第三届计算机技术与发展国际会议 ICCTD2011)

会议地点: 成都

会议语种:英文

页码: 1150-1154

在线出版日期: 2011-11-25（万方平台首次上网日期，不代表论文的发表时间）