STUDIES ON THE KETOPROFEN-POLYBUTYLCYANOACRYLATE-NANOPARTICLES OF ZEDOARY TURMERIC OIL

摘要：

Objective: To investigate the optimum preparation conditions of the Ketoprofen-Ploybutylcyanoacrylate- Nanoparticles of zedoary turmeric oil (ZTO-PBCA-NP). Methods: The optimization of preparation process of ZTO-PBCA-NP was studied with the butylcyanoacrylate (BCA) as the polymeric materials, with ebedding ration as the evaluation index and with uniform design optimization ZTO-PBCA-NP preparation.Results: The multiple regression equation by the uniform design optimization ZTO-PBCA-NP preparation was Y= 179.157+24.958A1-182.328A2 -13.468A5 (R=0.9254, F= 32.114, P<0.01), the average ebedding ratio was between 84.90％ ± 2.40％ under optimum conditions.Conclusion: The Curcuma oil, BCA dosage and pH value are linear regression with the ebedding ratio of ZTO-PBCA-NP.The study screens out the optimum preparation conditions of ZTO-PBCA-NP.

关键词： Zedoary Turmeric Oil PBCA-NP Uniform Design Ebedding Ratio

作者: ZENG JIAN-HONG XU GANG-BIAO CHEN XU LUO XIAO-QIN QIN WAN-LING

作者单位: Central South University of Forestry and Technology,Changsha 410004,China Central South University of Forestry and Technology,Changsha 410004,China School of Pharmacy,Guilin School of Pharmacy,Guilin Medical College,Guilin 541004,China Guangxi Wanfeng Pharmaceutical Co. Ltd,Guilin 54100,China

会议类型: 国际会议

会议名称: 2011 3rd International Conference on Computer Technology and Development(2011第三届计算机技术与发展国际会议 ICCTD2011)

会议地点: 成都

会议语种:英文

页码: 1194-1198

在线出版日期: 2011-11-25（万方平台首次上网日期，不代表论文的发表时间）