Modelling Krebs Cycle as an Electrical Circuit
Biochemical metabolic pathways contain information regarding all the important biochemical reactions within a cell. A detailed knowledge of the kinetics of the various processes is important in many applied processes and simulation. Although detailed information about the various enzymes involved in the metabolic pathway are available in various databases, the actual computation of the various fluxes is difficult. In this report we propose an electrical circuit analogue for the well-known Krebs cycle, which can be useful in the kinetic studies for various components, both individually and also for the cycle as a whole. Electrical circuits are easier to analyse and study, as several useful tools are already available for this purpose. It is possible to study theoretically the stability conditions for the cycle as a whole. The Krebs cycle is essentially modelled as a blackbox equivalent to an electrical circuit.
Kalyani Korla Chanchal Mitra
University of Hyderabad, Hyderabad 500046, India
国际会议
杭州
英文
158-159
2012-04-02（万方平台首次上网日期，不代表论文的发表时间）