Oral and maxillofacial desmoid-type fibromatoses in an eastern Chinese population: a report of 20 cases
Objective. Primary desmoid-type fibromatoses arising from the oral and maxillofacial region are uncommon and hold the character of local invasion and regional recurrence. The purpose of this study was to analyze ihe clinicoepidemiologic characteristics of this rare disease in an eastern Chinese population. Study design. Epidemiological and clinicopathological data on 20 patients were reviewed from the hospital records and analyzed accordingly. Results. Twelve males and 8 females with a ratio of 3:2 were involved. The mandible was the most common site of presentation. Suspected malignant change was found in 6 cases and an extremely high recurrence rate was also found in up to 53％. Abnormally high blood levels of alkaline phosphatase were found in 65％ of patients, which had a close relation with tumor malignant change. Conclusion. Chinese people are more susceptible to desmoid-type fibromatoses and are at an extremely high risk of regional malignant change. Elevated serum alkaline phosphatase levels may be taken as an indicator for malignant transformation.
Ruan Min Zhang Zun Wang Lizheng Dong Minjun Liu Shengwen Yang Wenjun Zhang Chenping
Department of Oral & Maxillofacial Surgery, Ninth Peoples Hos-pital, Shanghai Jiao Tong University, Department of Stomatology and Affiliated I Peoples Hospital, School of Medicine, Shanghai Jiao Tong Department of Oral Pathology, Affiliated 9 Peoples Hospital, School of Medicine, Shanghai Jiao Tong Department of Radiology and Affiliated 9 Peoples Hospital, School of Medicine, Shanghai Jiao Tong U Department of Oral & Maxillofacial Surgery, Ninth Peoples Hospital, Shanghai Jiao Tong University,
国际会议
上海
英文
363-368
2011-12-28（万方平台首次上网日期，不代表论文的发表时间）