Effect of pH on optical properties during blood coagulation progress by optical coherence tomography

摘要：

Optical coherence tomography (OCT) has been used to evaluate blood coagulation process and is proved efficiently by using OCT signal slope and 1/e light penetration depth (Dl/e). The purpose of this study is to investigate the effect of pH on the two optical properties of whole blood during in vitro clot formation under static by optical coherence tomography. After the addition of 0.9％ (w/v) sodium chloride solution with pH=6, 7,8,9, OCT signal slope (OCTSS) have a total decrease of 6.98％, 4.07％, 4.16％, 3.69％ after 60-min coagulation, and the blood clotting time are 985, 1041, 1065, 967, respectively. Our results suggest that when blood pH was lower or higher than normal value, the blood clotting time shows a decrease and the process of blood coagulation appears abnormal.

关键词： blood pH blood coagulation Optical coherence tomography optical parameters

作者: Feifei Fu Jia Lin Xiangqun Xu

作者单位: School of Science Zhejiang Sci-Tech University Hangzhou, China

会议类型: 国际会议

会议名称: 2011 4th International Conference on Biomedical Engineering and Informatics(第四届生物医学工程与信息学国际会议 BMEI 2011)

会议地点: 上海

会议语种:英文

页码: 269-272

在线出版日期: 2011-10-15（万方平台首次上网日期，不代表论文的发表时间）