Functional Photoacoustic Imaging Of Osteoarthritis In The Finger Joints
We present pilot clinical evidence that multispectral quantitative photoacoustic tomography (qPAT) has the potential to detect osteoarthritis (OA) in the finger joints. In this pilot study, 2 OA patients and 4 healthy volunteers were enrolled, and their distal interphalangeal (DIP) joints were examined photoacoustically by a multispectral PAT scanner. Images of tissue physiological/functional parameters including oxy-hemoglobin, deoxy-hemoglobin, oxygen saturation and water content along with tissue acoustic velocity of all the examined joints were simultaneously recovered using a finite element reconstruction algorithm for multispectral photoacoustic measurements. The recovered multispectral photoacoustic images show that the OA joints have significantly elevated water content, decreased oxygen saturation, and increased acoustic velocity compared to the normal joints.
photoacoustic imaging osteoarthritis
Jiaying Xiao Jingtian Tang GuangYin Lu Zhensen Chen
School of Geosciences and Info-Physics Engineering Central South University Changsha 410083, China
国际会议
上海
英文
299-303
2011-10-15（万方平台首次上网日期，不代表论文的发表时间）