Image-Based Computational Hemodynamics of Distal Aortic Arch Recoarctation Following the Norwood Procedure
Currently, few applications of computational hemodynamics predict outcomes after palliative surgery for congenital heart defects such as hypolastic left heart syndrome in infants. Here, we report on three- dimensional imaging methods for modeling recoarctation that commonly occurs in the distal aortic arch following the Norwood procedure. We used computer-aided design to simulate seven stages of increasing stenosis, analyze the resulting hemodynamics, and visualize the impairment of blood flow. A disproportionate drop in pressure occurred when stenosis reached 20％ of the cross-sectional area of the descending aorta. The corresponding decrease in blood flow in the descending aorta was relatively small, however. Accordingly our findings suggest a reasonable approach to this phenomenon is watchful waiting rather than immediate surgical intervention. Such patient-specific predictions appear to be valuable for minimizing the risks of corrective surgery. These methods also may be applied to procedures for alleviating other congenital heart defects.
medical imaging computer-aided design computational fluid dynamics recoarctation hemodynamics Norwood procedure
JLLIU YQIAN KITATANI A MURAKAMI R SHIURBA TMYAKOSHI KMYAJI MUMEZU
Center for Advanced Biomedical Sciences, TWIns Waseda University Tokyo, Japan Australian School of Advanced Medicine Macquarie University Sydney, Australia Graduate School of Medicine The University of Tokyo Tokyo, Japan Graduate School of Medicine The Universityof Tokyo Tokyo, Japan School of Medicine Kitasato University Kanagawa, Japan
国际会议
上海
英文
318-323
2011-10-15（万方平台首次上网日期，不代表论文的发表时间）