Measurements of light energy distribution in pathological lesions using focused photoacoustic imaging
Generally, measuring the location and optical properties of pathological lesions in biological tissue is pretty helpful for accurate diagnosis and effective treatment of diseases. In order to have a further diagnosis, it is necessary to implement a further study on the distribution of light energy inside the pathological lesions. In this paper, we focused on the localization of lesions and measurements of light energy distribution inside the lesions using photoacoustic (PA) imaging. Ink blocks were used to mimic the lesions in the sample. Some graphite rods were utilized as probes to help mapping the light distribution in lesions. As a result, our experiments are able to locate specific lesions in the sample. Furthermore, this method can be used to uncover the light energy distribution inside the lesions and to analyze qualitatively the influences of optical properties of the lesions and the ambient medium on the light energy distribution. It is promising for our method in diagnosing tumors in the early stage and identifying benign and malignant lesions in clinical applications.
photoacoustic imaging light energy distribution pathological lesions localization of lesions
Zhiping Zeng Zhifang Li Wenming Xie Jianying Zhang Hui Li
Key Laboratory of OptoElectronic Science and Technology for Medicine, Ministry of Education,Fujian Provincial Key Laboratory of Photonic Technology,School of Physics and OptoElectronics Technology, Fujian Normal University,Fuzhou, Fujian 350007, China
国际会议
上海
英文
371-374
2011-10-15（万方平台首次上网日期，不代表论文的发表时间）