Effectiveness Research of Deep Brain Stimulation Operation for Patients with Parkinsons Disease Based on Polar Coordination System with Varied Origin
Parkinsons disease (PD) is a common disease of central nervous system among the elderly, and its complex symptoms bring up some difficulties for the clinical diagnosis. And Deep Brain Stimulation (DBS) is an effective treatment method for patients with Parkinsons disease. In this study, a method based on polar coordination system with varied origin was proposed to quantitatively evaluate the availability of DBS operation for patients with Parkinsons disease. Totally, seven patients with Parkinsons disease were participated in the spiral drawing experiment and their scores under Unified Parkinsons disease Rating Scale (UPDRS) were also recorded. According to the characteristics of hand movement in spiral drawing, a set of parameters were defined and calculated before and after DBS operation. Compared with the UPDRS scores, experimental results showed that this method of evaluation was consistent with the clinical diagnosis. The proposed method based on polar coordinate system with varied origin is effective in clinical diagnosis, and it provides a basis for quantitative evaluating the effectiveness of surgery and treatment.
Parkinsons disease Polar coordinate system with varied origin Deep brain stimulation operation Unified Parkinsons Disease Rating Scale Quantitative effectiveness evaluation
Min Wang Bei Wang Junzhong Zou Jian Zhang Masatoshi Nakamura
Department of Automation, School of Information Science and Engineering East China University of Sci Department of Advanced System Control Engineering, Saga University, Saga 840-8502, Japan
国际会议
上海
英文
727-731
2011-10-15（万方平台首次上网日期，不代表论文的发表时间）