Model-Free Marginal Orientation Distribution Function Reconstruction in Single-Shell Q-Ball Imaging
Q-Ball imaging (QBI) is a successful and widely used high angular resolution diffusion imaging (HARDI) technique which can compute orientation distribution function (ODF). This technique only needs single shell HARDI data and does not require any assumption about the diffusion signal outside the sampling sphere. However the originally proposed ODF (the radial project of the probabihty density function (PDF)) is not a true ODF. In contrast the marginal ODF with solid angle consideration, represents a true ODF with a correct probabilistic interpretation. In this paper a novel model-free and single-shell HARDI method for analytical reconstruction of the marginal ODF based on Funk-Radon transform (FRT) is proposed. In other words, a transformation of QBI for marginal ODF is proposed in this paper. While theres also a proportional factor introduced by FRT. Its complexity is comparable to that of the original QBI. Finally the present paper verify the algorithm and show the improved result of my method compared to the original QBI on synthetic data, biological phantom data and real human brain data.
diffusion-weighted MRI Q-Ball Imaging HARDI orientation distribution function
Na Zhang
Department of Mathematics Zhejiang University Hangzhou, China
国际会议
上海
英文
966-969
2011-10-15（万方平台首次上网日期，不代表论文的发表时间）