Intermediate Alternating Electric Fields Device for enhancing chemotherapy of cancer: Device Development and the Biological Effects
Recent studies have shown that intermediate frequency alternating electric fields stimulation is a promising alternative treating strategy for proliferative diseases including tumors. This article presents a safe electronic device which is capable of generating low intensity electric fields of sine, square, triangle wave from 100 kHz to 1MHz. The electric fields are generated by a waveform generator, filtered by a Butter-worth low pass filter, amplified by a two-order amplifier, and then equipped with an array of platinum electrodes. An embedded-software runs on ATmegal28 and a touch screen provides a user-friendly interface for the operator. The intensity of electric fields is simulated by CST STUDIO SUITE? using Finite Integration Technique (FIT). By the use of the device, we show that alternating intermediate frequency electrical stimulation enhanced chemotherapy of breast cancer cells.
alternating electric fields cancer device development chemotherapy enhancing
Rui Ting Liu Zi Han Zhuo Yue Yu Yu Fang Jie Qiong Tong Hong Guo Jin Tian Tang
Key Laboratory of Particle & Radiation Imaging (Tsinghua University), Ministry of Education Department of Engineering Physics, Tsinghua University Beijing, China
国际会议
上海
英文
1128-1132
2011-10-15（万方平台首次上网日期，不代表论文的发表时间）