The Effect of Mechanical Strain on Proliferation of Lung Cancer A549 Cells And Squamous Carcinoma of Tongue Tca8113 Cells

摘要：

Using FX-4000 strain unit, the proliferation of human lung adenocarcinoma A549 cells and Squamous Carcinoma of Tongue Tca8113 Cells that underwent different mechanical strain were studied. Flow Cytometer was adopted to investigate the proliferation of A549 cells and Tca8113 cells. Experimental results indicated that cell proliferation index (PI) reduced significantly after A549 cells and Tca8113 cells were subjected to square wave with 15％ elongation at frequency 0.5Hz for 4h , the PI had no distinct difference for sine wave and triangle wave treated A549 cells and Tca8113 cells when compared with the control group. It was indicated that cyclic stretch could inhibit the proliferation of A549 cells and Tca8113 cells , the waveform play important roles in inhibiting proliferation.

关键词： cyclic stretch waveform lung adenocarcinoma A549 cells Squamous Carcinoma of Tongue Cells proliferation

作者: Hua QU Peng GAO

作者单位: College of Science Tianjin Polytechnic University Tianjin, China Institute of Applied Mechanics and Biomedical Engineering Taiyuan University of Technology Taiyuan,

会议类型: 国际会议

会议名称: 2011 4th International Conference on Biomedical Engineering and Informatics(第四届生物医学工程与信息学国际会议 BMEI 2011)

会议地点: 上海

会议语种:英文

页码: 1545-1548

在线出版日期: 2011-10-15（万方平台首次上网日期，不代表论文的发表时间）