The integration analysis of multiple species phosphorylation sites

摘要：

Protein phosphorylation plays a key role in sucrosemediated transcriptional regulation of a phloemspecific proton-sucrose symporter. We evaluate the conservation of phosphorylation sites and its surrounding amino acids stretch through statistic analysis in this paper. Ten eukaryotic model species protein sequences were downloaded and the sequences which have ortholog were reserved for the anaysis. To compare the conservation of phosphorylation sites and its flanking sequences, we create two indexes named conservation score (C-score) and conservation Z-score (CZ-score) to evaluate the conservation of phosphorylation sites and its flanking sequences. The result shows that phosphorylated sites may be much better conserved than the unphosphorylated sites. The flanking sequences of phosphorylation site dont reflect the same trend.

关键词： component comservation phosphorylation sites flanking sequences

作者: Ying Liu

作者单位: Foundation department ZheJiang TongJi Vocational College of science and technology HangZhou, China

会议类型: 国际会议

会议名称: 2011 4th International Conference on Biomedical Engineering and Informatics(第四届生物医学工程与信息学国际会议 BMEI 2011)

会议地点: 上海

会议语种:英文

页码: 1621-1625

在线出版日期: 2011-10-15（万方平台首次上网日期，不代表论文的发表时间）