Real-time Monitoring on Peptide Synthesis by GMR Biosensors

摘要：

In this work, a real-time monitoring system has been developed. The micro-optic device applying the guided-mode resonance (GMR) effect has been designed and fabricated. By combining a simple and low cost microfluidic channel, the GMR measurement for detecting peptide synthesis reaction has been explored. It is able to determine whether or not the chemical reaction reacts and how far the chemical reaction arrived. In addition, the kinetics analysis for the peptide synthesis has also been discussed. It is successfully demonstrated that the GMR device is capable of monitoring the process of peptide synthesis in real time.

关键词： guided-mode resonance peptide synthesis kinetics analysis waveguide real-time monitoring system

作者: Jiann-Hwa Lue Ting-Jou Ding Tsung-Hsun Yang Jenq-Yang Chang Wen-Yih Chen

作者单位: Department of Optics and photonics National Central University Chungli 32001, Taiwan Department of Chemical and Materials Engineering National Central University Chungli 32001, Taiwan

会议类型: 国际会议

会议名称: 2011 4th International Conference on Biomedical Engineering and Informatics(第四届生物医学工程与信息学国际会议 BMEI 2011)

会议地点: 上海

会议语种:英文

页码: 1870-1873

在线出版日期: 2011-10-15（万方平台首次上网日期，不代表论文的发表时间）