Hypoglycemic effect of saponin extracts from leaves of Momordica charantia

摘要：

In order to investigate hypoglycemic effects of Momordica charantia(MC) leaves saponins, saponins with purity of 86.0％ were extracted from leaves of MC.The extracts were used to treat hyperglycemic rats and the damaged insulinoma cell RIN-M5F in vitro. The effects of MC leaves extracts on the metabolic parameters (serum glucose, insulin, glycogen, Superoxide Dismutase(SOD) activity and Malonedialdehyde (MDA) levels of hyperglycemic rats and the effects on RIN-M5F cells were observed. The results showed that there was a significant increase in serum insulin and glycogen,accompanied by a decrease in serum glucose and MDA in treated rats with MC leaves saponins. And the extracts also exhibited obvious protection and repairation effects on RIN-M5F cells.

关键词： Momordica charanti leaves saponins xtraction hypoglycemic

作者: Jin-fuLiu YanCui Qing-fengHe Ling-ling You

作者单位: Department of Food Science and Engineering Tianjin Agireculture University Tianjin ,China

会议类型: 国际会议

会议名称: 2011 4th International Conference on Biomedical Engineering and Informatics(第四届生物医学工程与信息学国际会议 BMEI 2011)

会议地点: 上海

会议语种:英文

页码: 1986-1989

在线出版日期: 2011-10-15（万方平台首次上网日期，不代表论文的发表时间）