A Clinical Omics Database Integrating Epidemiology, Clinical, and Omics Data for Colorectal Cancer Translational Research
To provide an open translational research platform to narrow the gap between clinical practice and laboratory research of colorectal cancer, we construct a more comprehensive clinical omics database integrating not only clinical and omics data, but also epidemiology data from more than 150 patients. Based on this integrated database, we provide query, integrated view, and data analysis for clinical physicians, molecular biologists, and other researchers related with colorectal cancer translational research, facilitating the investigation of genotype-phenotype correlations in colorectal cancer and the application of basic research results in clinical practice. This paper presents our present work on the clinical omics database. Specifically, we apply EAV-ER model in the concept model design of this integrated database to accommodate the dynamic and sparse nature of biomedical data.
clinical omics database epidemiology EAV-ER model translational research colorectal cancer
Ling Zheng Li Wang Da Wang Ning Deng Xudong Lu Huilong Duan
College of Biomedical Engineering and Instrument Science of Zhejiang University The Key Laboratory o Department of Colorectal Surgery, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, China
国际会议
上海
英文
2040-2044
2011-10-15（万方平台首次上网日期，不代表论文的发表时间）