Effects of Blood Flow on High Intensity Focused Ultrasound Ablation
With the benefits of high accuracy and non-invasive implementation, high intensity focused ultrasound (HIFU) is a promising medical procedure to heat and destroy pathogenic tissue rapidly. However, the relation between the power emitted by the ultrasound transducer and the energy arriving at the target area is complex, interfered by several factors such as the properties of tissue, obstacles of hard tissues or vascularization. In this study, a finite element model was used to simulate the propagation process of focused ultrasound inside tissue phantom and passing the perfused vascular. Then, the resultant sound pressure distribution provided the heat source for heat transfer process simulation. The simulation results were validated with thermocouple measurements in egg white phantoms. This study demonstrated an efficient methodology for estimating the thermal effects in HEFU hyperthermia therapy, especially in the region with large blood vessel. This study will be useful in minimizing difficulties and risks in HIFU induced hyperthermia treatment and facilitate the extension from laboratory to clinic use.
High intensity focuced ultrasound ultrasound propagation blood flow hyperthemia simulation
Shaozhen Song Jing Gao Zhihong Huang Dong-Sheng Jeng Huijie Zhang
School of Engineering, Physics and Mathematics University of Dundee Dundee DD1 4HN, Scotland, UK
国际会议
上海
英文
2290-2293
2011-10-15（万方平台首次上网日期，不代表论文的发表时间）