Characterization of Oscillating Nano Knife for Single Cell Cutting by Nanorobotic Manipulation System inside ESEM

摘要：

In this paper, a novel oscillating nano knife for single cell cutting at its native state was proposed. The nano knife with a small edge angle 5° was fabricated from a commercial AFM cantilever by focused ion beam (FIB) etching. The spring constant of the nano knife was calibrated by nanorobotic manipulation method. A piezo actuator was employed to generate the vibration of the nano knife. The oscillating amplitude response to the applied voltage was calculated based on the realtime image observation. Single yeast cell (W303) cutting using oscillating nano knife was performed based on the nanorobotic manipulation system inside an environment-SEM. The maximum cutting forces and the slices angle were measured from the deformation of the nano knife beam and the single cell. The result showed the oscillating nano knife was capable and effective for single cell cutting task.

作者: Yajing Shen Masahiro Nakajima Seiji Kojima Michio Homma Yasuhito Ode Toshio Fukuda

作者单位: Depart- ment of Micro-Nano Systems Engineering,Nagoya University,Japan Center for Micro-nano Mechatronics,Nagoya University,Japan Division of Biological Science,Graduate School of Science,Nagoya University,Japan

会议类型: 国际会议

会议名称: 2011 IEEE International Conference on Robotics and Automation(2011年IEEE世界机器人与自动化大会 ICRA 2011)

会议地点: 上海

会议语种:英文

页码: 4133-4138

在线出版日期: 2011-05-09（万方平台首次上网日期，不代表论文的发表时间）