Next Generation Large-Scale Chronically Implantable Precision Motorized Microdrive Arrays for Freely Behaving Animals
Multiple single-unit recording has become one of the most powerful in vivo electro-physiological techniques for investigating neural circuits. The demand forsmall and lightweight chronic recording devices with large number of electrodes has been increasing. However, conventional techniques do not allow fine adjustments to be made over large number of electrodes across multiple brain regions without disturbing the recording subject. Here, we have developed a large-scale motorized microdrive array to record from freely behaving animals. It has design flexibility and allows for remote adjustment of a large number of electrodes at a very fine resolution. Versions of the microdrive array were chronically implanted on both rats (21 microdrives) and mice (7 microdrives) and relatively long term recordings were taken. In this talk, current status of the new technology and future directions will be presented.
Motorized microdrive array Large-scale Chronically implantable microdrive Freely behaving animals Rats Mice
Jun Yamamoto
Departments of Brain and Cognitive Sciences and Biology, RIKEN-MIT Neuroscience Research Center, The Picower Institute for Learning and Memory, Massachusetts Institute of Technology,Cambridge, MA 02139, USA
国际会议
The Second International Conference on Cognitive Neurodynamics--2009(第二届国际认知神经动力学会议)
杭州
英文
67-72
2009-11-15（万方平台首次上网日期，不代表论文的发表时间）