A Modeling Study of Glutamate Release of NMDA Receptors

摘要：

In this chapter we will use a mathematical model to simulate spontaneous and evoked neurotransmission to determine how receptor location on presynaptic density can activate distinct sets of NMDA receptors and signal independently to the postsynaptic side. We will also examine how the release rate of the neurotransmitter Glutamate will affect post-synaptic currents by varying the fusion pore size at the presynaptic side.

关键词： Synapse modeling Neurotransmission Independent signaling NMDA receptors Diffusion equation Chemical synapses

作者: Justin Blackwell Jianzhong Su Ege Kavalali

作者单位: Department of Mathematics, The University of Texas at Arlington, Arlington, TX 76019, USA

会议类型: 国际会议

会议名称: The Second International Conference on Cognitive Neurodynamics--2009(第二届国际认知神经动力学会议)

会议地点: 杭州

会议语种:英文

页码: 301-306

在线出版日期: 2009-11-15（万方平台首次上网日期，不代表论文的发表时间）