Functions of Shallow vs. Deep Theta-Nested Gamma in Object Recognition
Using a network of excitatory pyramidal cells and inhibitory interneurons with fast and slow GABAa kinetics, we have successfully reproduced our recent experimental observations from local field potential and multiunit activity recordings from the sheeps inferior temporal cortex during learning of visual discrimination tasks. Both experimental and numerical results showed that following learning, theta wave amplitude is significantly increased and its phase is more highly correlated with the amplitude of gamma wave during stimulus presentation. The increased correlation between the theta phase and the gamma amplitude is a consequence of theta-nested gamma. Importantly, we have used the model to show that learning effects can be reproduced simply by altering the sensitivity of NMDA receptors and that the resultant shallowing of theta-nested gamma potentiates responses made by downstream neurons.
Integrate-and-fire neural network Theta-nested gamma rhythm AMPA receptors GABAa receptors Time-frequency spectrum
Xuejuan Zhang Yang Zhan Keith M. Kendrick
School of Mathematical and Physical Sciences, Zhejiang Normal University, Jinhua 321004,P.R. China
国际会议
The Second International Conference on Cognitive Neurodynamics--2009(第二届国际认知神经动力学会议)
杭州
英文
553-562
2009-11-15（万方平台首次上网日期，不代表论文的发表时间）