Transcriptomic Analysis of the Responses of Escherichia coli to Chlorine-Based Oxidative Stress
1 Introduction Chlorination is one of the most widely used processes for microbial control in both drinking water and wastewater treatment processing. However, some cells exposed to chlorine undergo sublethal stress or injury while maintaining metabolic activity. Public health may be threatened because chlorine-injured bacteria are capable of regaining virulence in aquatic environments as well as regaining culturability upon removal from chlorine stress and introduction to a more favorable environment. The linkage between the cells defense mechanism against chlorine and the remainder of the cells metabolism has not been elucidated. Microarray-based transcriptome analysis enables us to simultaneously and globally examine the complete transcriptional response at the genomic level. In the present study, we investigated the dynamics of global gene expression profiles during the cellular response of Escherichia coli to oxidative stress induced by chlorine (0.2 mg/1)
Shu-Xu WU Dan LI Miao HE
State Key Joint Laboratory of Environmental Simulation and Pollution Control, School of Environment, Tsinghua University, Beijing China, 100084
国际会议
北京
英文
235-236
2011-11-24（万方平台首次上网日期，不代表论文的发表时间）