Spontaneous oscillations of cerebral oxygenation signal and its correlation with Transcranial Doppler Hemodynamic Parameters

摘要：

The objective of this study is to assess the correlation between the prefrontal cerebral oxygenation oscillations measured by near-infrared spectroscopy (MRS) and cerebral artery hemodynamic parameters as measured by transcranial Doppler (TCD). The cerebral oxygenation signal was monitored for 10 minutes from the left prefrontal lobe using MRS. TCD monitoring was performed to measure the hemodynamic parameters including end diastolic, peak systolic, and mean cerebral blood flow velocities. With spectral analysis based on wavelet transform of NIR signal, five frequency intervals were identified (Ⅰ, 0.005-0.02 Hz,Ⅱ, 0.02-0.06 Hz,Ⅲ, 0.06-0.15 Hz, Ⅳ, 0.15-0.50 Hz and Ⅴ, 0.50-2.0 Hz). Significant negative correlation was found between the cerebral Hb and HbO2 oscillations in frequency intervals III(0.06-0.15Hz),IV (0.15-0.5Hz),V(0.5-2 Hz) and the mean velocity in left middle cerebral artery (MCA)(p<0.05).The results suggested that the cerebral oscillations measured from the fronal lobe were closely related to the vessel stiffness of MCA.

作者: Zengyong Li Qing Xin Jianping Li

作者单位: School of Mechanical Engineering, Shandong University, Jinan, 250061 P.R. China Hospital of Shandong University, Jinan, 250061 P.R.China

会议类型: 国际会议

会议名称: 2011 International Symposium on Bioelectronics and Bioinformatics(第二届国际生物医学电子学与生物信息学学术会议 ISBB 2011)

会议地点: 苏州

会议语种:英文

页码: 100-102

在线出版日期: 2011-11-03（万方平台首次上网日期，不代表论文的发表时间）