Digital Holographic Phase-Contrast Microscopy for 3D Imaging of Gastric Cancer Cells
Digital holographic phase-contrast microscopy, a new imaging microscopy, is the combination of digital holography with microscopy. It possesses some unique advantages, e.g. non-destructive, non-invasive and quantitative analysis, and it can be used to image for phase-type objects. In this paper, gastric cancer cells at different stages of cell division were studied employing transmission experimental setup, and the intensity image and phase image of the cells were obtained. The cell sizes were calculated and the cell structures were analyzed according to the intensity and phase images. The result shows that digital holographic phase-contrast microscopy can be used to 3D imaging of microscopic phase object under marker-free condition and real-time quantitative measurement. The technique has a strong potential in biomedical applications.
Cuiying Hu Jingang Zhong Jiawen Weng Guangrong Yan
Department of Physics, Jinan University,Guangzhou 510632, China Department of Optoelectronic Engineering,Jinan University, Guangzhou 510632, China Key Laboratory of Department of Optoelectronic Engineering, Jinan University, Guangzhou 510632, China Institutes of Life and Health Engineering,Jinan University, Guangzhou 510632, China
国际会议
2011 International Symposium on Bioelectronics and Bioinformatics(第二届国际生物医学电子学与生物信息学学术会议 ISBB 2011)
苏州
英文
271-274
2011-11-03（万方平台首次上网日期，不代表论文的发表时间）