THE FORMATION OF REACTIVE OXYGEN SPECIES DURING POLYCHLORINATED BIPHENYL METABOLISM IN HEPG2 CELLS

摘要：

The cellular toxicity of polychlorinated biphenyls (PCBs) quinones was investigated. It is proved that the exposure of PCB quinones cause oxidative damages in HepG2 cells, by loss of cell viability, free radicals and lipid peroxidation product generation, and the damage of antioxidant defense system. However, antioxidant DH-LA provides significant protection by against PCB quinones induced oxidative damages.

作者: Liu Jing Liu Lichao Ma Xiaoyan Tian Xingguo Dong Hui Song Yang

作者单位: Key Laboratory of Luminescence and Real-Time Analysis, Ministry of Education, College of Pharmaceutical Sciences,Southwest University, Chongqing 400715, China

会议类型: 国际会议

会议名称: The 7th International Forum on Post-Genome Technologies and China-Japan-Korea Summit on Natural Products(第七届国际后基因组技术论坛及中日韩天然产物论坛 IFPT)

会议地点: 重庆

会议语种:英文

页码: 58-59

在线出版日期: 2011-10-28（万方平台首次上网日期，不代表论文的发表时间）