FABRICATION AND APPLICATION OF THE SELF-ASSEMBLED γ-Fe2O3@AU NANOCOMPOSITES WITH LOW FLUORESCENCE BACKGROUND
The gold-coated magnetic nanocomposites (MNPs) have attracted great interest due to their various properties, such as easy magnetic separation, good biocompatibility, and optical properties and so oa The gold-coated MNPs with low fluorescence background can be employed to be carriers to develop a highthroughput bioassay of fluorescence detection based on bead array. In present work, we synthesized a kind of gold-coated magnetic nanocomposites γ-Fe2O3 @ Au (GMNPs) with low fluorescence background via self-assembled process. Moreover, the GMNPs modified by streptavidin (SAGMNPs) can combine with biotinylated fluorescent oligonucleotide through the reaction between biotin and streptavidin (SA), which will possess great potential application in molecular analysis with fluorescence.
Gold-coated magnetic nanocomposites γ-Fe2O3@Au Self-assembled process Fluorescence
Jiang Hongrong Zeng Xin He Nongyue
State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering,Southeast University, Nanjing 210096, China
国际会议
重庆
英文
95-96
2011-10-28（万方平台首次上网日期，不代表论文的发表时间）