TRANSLOCATION OF Ji-DNA THROUGH A SOLID-STATE NANOPORE

摘要：

Solid-state nanopores have been proven a new category of sensors for individual unlabeled biopolymer detection and characterization. It provides a new possible way for fast and low cost DNA sequencing. Until now, samples are mainly focused on doublestranded DNA (dsDNA) molecules. In this work, X-DNA molecules are driven through a nanopore, 35 nm in diameter by electric field. We found that the corresponding blockage current is typically 167 pA, and translocation time is around 3. 5 ms. Based on previous results, we believe that nanopore is no doubt a promising fast and efficient DNA detection technique in the future.

关键词： solid-state nanopore translocation translocation time current blockage

作者: Wu Hongwen Zhao Zhiliang Liu Liping Sun Feng Kong Jinglin Ye Xiaofeng Chen Yiwen Liu Quanjun

作者单位: State Key Laboratory of Bioelectronics, Southeast University, Nanjing 210096, China Department of Physics, Southeast University, Nanjing 210096, China

会议类型: 国际会议

会议名称: The 7th International Forum on Post-Genome Technologies and China-Japan-Korea Summit on Natural Products(第七届国际后基因组技术论坛及中日韩天然产物论坛 IFPT)

会议地点: 重庆

会议语种:英文

页码: 141-143

在线出版日期: 2011-10-28（万方平台首次上网日期，不代表论文的发表时间）