ICAM-1 EXPRESSION ALTERATION IN SCIATIC NERVES FOLLOWING NERVE INJURY
The injuries of the peripheral nerve are the results of trauma, disease and surgical procedures that require section of peripheral nerves to gain access to the surgical site. Recent studies provide evidence that Intercellular adhesion molecule-KICAM-1) is involved in cell recruitment during Wallerian degeneration after peripheral nerve injury. In our studies, two different injury models (crush and transect) for peripheral nerve regeneration were used. We investigated the dynamic changes of ICAM-1 expression in sciatic nerves following sciatic nerve injury. Double labeling demonstrated the presence of ICAM-1 within both Schwann cells and nerve blood vein endothelia cells in sciatic nerve after injurym, suggesting that ICAM-1 might be correlated with the function of Schwann cells about myelinogenesis and nerve regeneration.
ICAM-1 nerve injury sciatic nerve
Yang Junling Yao Dengfu Wu Wei Qiu Liwei Sai Wenli Zhang Haijian
Research Center of Clinical Medicine. Affiliated Hospital of Nantong University, Nantong, China
国际会议
重庆
英文
188-190
2011-10-28（万方平台首次上网日期，不代表论文的发表时间）