PROTEOMICS ANALYSIS OF SERUM PROTEIN PROFILING IN CERVIAL CANCER PATIENTS BY DIGE

摘要：

A proteomic study of serum protein expression in cervical cancer and non-cancer patients, including cervical intraepithelial neoplasia (CIN) and cervicite, was performed with two-dimensional difference gel electrophoresis (2D-DIGE) and MALDITOF-TOF analysis. Some differentially expressed proteins were detected according to the image analysis, and these proteins of interest were identified by tandem mass spectrometry. A literature review was performed for all identified proteins, and these proteins may be involved into the cancer metastasis through different signal pathways.

关键词： Cervical cancer Cervical intraepithelial neoplasia Cervicite 2D-DIGE Proteomics

作者: Ye Nengsheng Duan Caiying Gu Xuexin

作者单位: Department of Chemistry, Capital Normal University, Beijing 100048, China

会议类型: 国际会议

会议名称: The 7th International Forum on Post-Genome Technologies and China-Japan-Korea Summit on Natural Products(第七届国际后基因组技术论坛及中日韩天然产物论坛 IFPT)

会议地点: 重庆

会议语种:英文

页码: 205-207

在线出版日期: 2011-10-28（万方平台首次上网日期，不代表论文的发表时间）