RECOMBINATION CYTOGLOBIN ANTI-OXIDATION AND ITS BIOLOGICAL EFFECTS
Molecular Medicine Engineering Research Center of the Ministry of Education, Huaqiao University,Quanzhou 362021, China A preliminary research study on anti-oxidan of recombination cytoglobin (rCygb) and its biolobical effects by H2O2 oxidative stress model of mouse embryonic fibroblast (MEF), skin aging model caused by continuous subcutaneous injection D-gal in mouses and skin burn model in rats. The results showed that rCygb could improve activities of total superoxide dismutase (T-SOD) and glutathione peroxidase (GSHPx), reduce activity of lactate dehydrogenase (LDH) and reduce level ofmalondialdehyde (MDA). Skin biopsy showed rCygb could promote angiogenesis, increase expression of collagen and anti-inflammatory. The results of this study showed that rCygb could improve the oxygen free radical scavenging ability, delay aging and promote wound healing.
rCygb anti-oxidation skin aging wound healing
Li Zhaofa Hui Erjing Wang Qizhao
Institute of Molecular Medicine, Huaqiao University, Quanzhou 362021, China Molecular Medicine Engin Institute of Molecular Medicine, Huaqiao University, Quanzhou 362021, China
国际会议
重庆
英文
211-213
2011-10-28（万方平台首次上网日期，不代表论文的发表时间）