Developmental Toxicity of Bisphenol A on Zebrafish Embryos

摘要：

To estimate the aquatic toxicity of Bisphenol A (BPA) , a static test using zebrafish (Danio rerio) embryos was carried out according to the Organization for Economic Cooperation and Development (OECD) guideline. The concentrations to cause 50% mortality (LCjo) in embryos at 24 hours post fertilization (hpf) and 48 hpf were calculated to be 15.01 mg/L and 18.04 mg/L, respectively. Nonfatal endpoints were also recorded. The results indicate that BPA has developmental toxicity on zebrafish embryos. The fish embryo toxicity test is a feasible method to assess the toxicity of BPA.

作者: Jun YAN Chuanlu HU Zhuge XI

作者单位: Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment & Food Safety,Institute of Hygiene and Environmental Medicine,Tianjin 300050, China

会议类型: 国际会议

会议名称: The 5th Session of the 13th Annual Meeting,CAST International Conference on Chemicals Risk Assessment of Environmental Hazard and Human Health(第13届中国科协年会第5分会场：化学物的环境危害与健康风险评估国际研讨会)

会议地点: 天津

会议语种:英文

页码: 140-142

在线出版日期: 2011-09-20（万方平台首次上网日期，不代表论文的发表时间）