Radiotracer Methods for Nanotoxicology Studies

摘要：

With the rapid development of nanoscience and nanotechnology, a wide variety of manufactured nanomaterials are now used in commodities, pharmaceutics, cosmetics, biomedical products, and industries. While nanomaterials possess more novel and unique physicochemical properties than bulk materials, they also have an unpredictable impact on human health. In nanotoxicology studies, it is essential to know the basic behavior of these newly designed materials in vivo, i. e. absorption, distribution, metabolism, and excretion. Radiotracer methods are especially well suited to such studies and have got the chance to demonstrate their enchantment. In this paper, radiolabeling methods for carbon nanomaterials, metallic and metal oxide nanoparticles, etc. are summarized and some applications of the radiolabeled nanomaterials in toxicology studies that carried out in our laboratory are reported.

作者: Zhiyong ZHANG Yuliang ZHAO Zhifang CHAI

作者单位: CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, 100049, China

会议类型: 国际会议

会议名称: The 5th Session of the 13th Annual Meeting,CAST International Conference on Chemicals Risk Assessment of Environmental Hazard and Human Health(第13届中国科协年会第5分会场：化学物的环境危害与健康风险评估国际研讨会)

会议地点: 天津

会议语种:英文

页码: 176-178

在线出版日期: 2011-09-20（万方平台首次上网日期，不代表论文的发表时间）