Signal enhancement for imaging ellipsomtry biosensor based on gold nanoparticles self-assembly layers

摘要：

This paper introduced a strategies for improving the sensitivity of biosensor based on imaging ellipsometry by adopting gold nanoparticles(GNPs) self-assembled array on silicon surface. GNPs with the diameter of ~5 nm were used, and the uniform GNPs layers were obtained as the substrate of biosensor. Compared with aldehyde group modified surface, the signal intensity of GNPs modified surface was improved 103 times for the interaction between human serum albumin bovine and its antibody.

作者: C.X.Wang G.Jin Y.Y.Chen

作者单位: Suzhou Institute of Nano-tech and Nano-bionics, Chinese Academy of Sciences Suzhou 215125,P.R.China Institute of Mechanics, Chinese Academy of Sciences, Beijing 100080, P.R.China

会议类型: 国际会议

会议名称: The First International Conference on Manipulation,Manufacturing and Measurement on the Nanoscale(第一届3M-NANO国际会议)

会议地点: 长春

会议语种:英文

页码: 1-3

在线出版日期: 2011-08-29（万方平台首次上网日期，不代表论文的发表时间）