Simulation of Silicon, Titanium and Tungsten Solid Nano-needles for Tissue and Cell Manipulation
Atomic force microscopy (AFM) is very promising technique nowadays to characterise the nano structures. The use of AFM in the biomedicine field is increasing rapidly, particularly for cell and tissue handling. This paper presents the design and simulation of solid nano needle attached with AFM cantilever for tissue and cell manipulation. Square base solid nano needle has been modelled on the tip of flexible cantilever. Silicon (Si), titanium (Ti) and tungsten (W) have been used for nano needle material and silicon nitride (SiN) is selected for cantilever. The length of needle is 104 nm and tip diameter is 250 nm. Base diameter of needle is 103 nm. Using ANSYS, structural analysis has been performed to investigate the mechanical properties and failure of nano needles during cell surgery. Axial and transverse forces have been applied on the needles to foresee the stress distribution and deflection. Presented data would provide useful information to develop the nano needle for cell surgery and tissue handling.
Muhammad Waseem Ashraf Shahzadi Tayyaba Dhananjay W.Bodhale Nitin Afzulpurkar
School of Engineering and Technology, Asian Institute of Technology (AIT), Bangkok, Thailand
国际会议
长春
英文
1-5
2011-08-29（万方平台首次上网日期，不代表论文的发表时间）