Design, Simulation and Fabrication of Hemofiltration System
(0) In this paper, novel design of hemofiltration system have been presented for the patients with kidney diseases. The proposed system consists of blood extraction and insertion device, blood filtration device, drug delivery device and control circuit. Silicon microneedles have been fabricated successfully using inductive coupled plasma (ICP) etching technology for drug delivery. Numerical simulation has been conducted in ANSYS. Fluidic analysis of aluminium (Al) based hemofilter has been performed to envisage the blood flow through hexagonal pores of filter. The flow rate of 488 μL/min has been obtained at driving pressure of 500 kPa through small filter section containing 81 pores. Each pore has diameter of 10 μm in the filter. New design of polyglycolic acid (PGA) based double lumen side open reservoir based microneedles integrated with piezoelectric actuator have been proposed as the blood transport device. Transient multifield analysis of fluidic device has been conducted. The flow rate of 475 μL/min has been observed through 25 microneedles at applied 125 V with 250 Hz on actuator. Presented work would provide useful information to develop automatic hemofiltration system for the patients who require regular and cyclic process of blood filtration.
Shahzadi Tayyaba Muhammad Waseem Ashraf Nitin Afzulpurkar
School of Engineering and Technology, Asian Institute of Technology (AIT), Bangkok, Thailand
国际会议
长春
英文
1-6
2011-08-29（万方平台首次上网日期，不代表论文的发表时间）