Study of temperature/glucose dually responsive nanocapsules with interpenetrating polymer network structure
The temperature/glucose dual stimuli responsive nanocapsules were fabricated in a five-step process. Firstly, the colloidal silica particles obtained by sol-gel method were modified by 3-(trimethoxysilyl)propyl methacrylate. Then, the silica/poly(N-isopropylacrylamide) (PNIPAM) core/shell structured nanoparticles were prepared by colloidal template polymerization using the silica particles as templates. Subsequently, crosslinked poly(acrylic acid) was incorporated into the crosslinked PNIPAM shell of silica/PNIPAM nanoparticles to form interpenetrating polymer network (IPN) structure. Later on, phenylboronic acid groups were introduced into their shells by the coupling reaction between the carboxylic acid groups of PAA components and 3-aminophenylboronic acids using carbodiimide as catalyst. Finally, the nanocapsules were formed via etching their silica templates using hydrofluoric acid. The FTIR and 5B NMR results confirmed that the nanocapsules were composed of PNIPAM and poly(N-phenylboronic acid acrylamide). Their hollow structure was identified by transmission electron microscopy (TEM). The temperature or glucose concentration dependent hydrodynamic diameters showed that the nanocapules had both temperature and glucose responsive properties.
WANG Congling XING Zhimin ZHA Liusheng
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials,Donghua University, Shanghai 201620, P.R.China
国际会议
2011 International Conference on Advanced Fibers and Polymer Materials(2011年先进纤维与聚合物材料国际会议 ICAFPM)
上海
英文
508-510
2011-08-15（万方平台首次上网日期，不代表论文的发表时间）