Study on reversibility of genetic toxicity of TDI in mice

摘要：

Study on whether genetic toxicity of toluene diisocyanate (TDI) is reversible. This paper detected Chromosomal aberrations and content of RNA & DNA. Chromosome aberration rate and the RNA/DNA ratio of TDI l/4LC_(50) and 1/2 LC_(50) dosing exposure group were higher than negative control group significantly (P<0.01). There was no significant difference between 1/4LC_(50) and 1/2LC_(50) (P> 0.05).The results showed that the damage of TDI on chromosomes and DNA was repairable, but can not be repaired completely.

作者: YU Miao JI Yu-bin

作者单位: Center of Research on Life Sciences and Environmental Sciences, Harbin University of Commerce, Harbi Center of Research on Life Sciences and Environmental Sciences, Harbin University of Commerce, Harbi

会议类型: 国际会议

会议名称: 2011 International Conference on Environmental Biotechnology and Materials Engineering(2011年环境生物技术与材料工程国际会议)

会议地点: 哈尔滨

会议语种:英文

页码: 905-909

在线出版日期: 2011-03-26（万方平台首次上网日期，不代表论文的发表时间）