Myeloperoxidase (MPO) Gene Polymorphism confers Cirrhotic Patients with Hepatopulmonary Syndrome

摘要：

In this study,we investigated the-463G/A promoter polymorphism of the MPO gene,in an attempt to explore the role of MPO in the pathogenesis of HPS caused by cirrhosis.The polymorphism of the MPO gene means the individual genotypes have different initial mRNA transcription activities and different expression levels,which further influences the activities of enzymes and results in the variation in disease susceptibility.This paper addresses gene polymorphisms play a key role in the development of HPS in cirrhotic patients.

作者: Jing Yu Bingquan Zhang Na Zhang Yanying Wang Yajuan Zhai Wenbing Wang

作者单位: The Second Affiliated Hospital of Qiqihaer Medical College.Qiqihaer 161000,P.R.China College of Food Engineering, Harbin University of Commerce, Harbin 150036, P.R.China Heilongjiang Provincial Hospital,Haerbin 150036,P.R.China

会议类型: 国际会议

会议名称: 2011 International Conference on Environmental Biotechnology and Materials Engineering(2011年环境生物技术与材料工程国际会议)

会议地点: 哈尔滨

会议语种:英文

页码: 1307-1311

在线出版日期: 2011-03-26（万方平台首次上网日期，不代表论文的发表时间）