The Immunomodulating Effect of Polysaccharides Purified from Pholiota adipose

摘要：

This study was designed to investigate the immunomodulating effect of polysaccharides purified from the fruit body of Pholiota adipose(PFBP). PFBP were extracted in 90℃ water bath and precipitated with 90％ ethanol. PFBP were orally administered at different dose to three different doses were administered to the normal group, NS group and the model group. The immunomodulating effect of PFBP was evaluated by measuring its effects on the weights of spleen and liver, delayed type hypersensitivity(DTH) response, the hemolysin level in serum and carbon expurgation level. Polysaccharide content purified from fruit body of Pholiota adipose was up to 72.88％. PFBP administered at different doses significantly improved the weights of the mouses spleen and live, as well as the level of carbon expurgation. Administered polysaccharides also had positive effect on DTH response and the hemolysin level in serum. These results suggest that PFBP may have immunomodulating potential for cylophosphamide.

作者: Dehai Li Changyan Sun Zhanbin Wang Zhqiang Wang

作者单位: Forestry School of Northeast Forestry University, 150040 , Harbin,PR China Dairy Industry Technical Development Center, 150086,Harbin,PR China

会议类型: 国际会议

会议名称: 2011 International Conference on Environmental Biotechnology and Materials Engineering(2011年环境生物技术与材料工程国际会议)

会议地点: 哈尔滨

会议语种:英文

页码: 1491-1495

在线出版日期: 2011-03-26（万方平台首次上网日期，不代表论文的发表时间）