Optimization of sulfated modification conditions in Undaria pinnatifida polysaccharides

摘要：

To optimize the sulfated modification conditions of Undaria pinnatifida polysaccharides (UPPS I B). UPPS I B was modified by chlorosulfonic acid-pyridine method. L9(34) orthogonal test was used to optimize the reaction temperature,reagent ratio and reaction time with the degree of sulfate group and carbohydrate content as index. The major factor was reaction temperature. The optimal modification conditions were that the reaction temperature was 60 ° C,the ratio of chlorosulfonic acid to pyridine was 1:2,and the reaction time was 1.5h. The sulfated UPPS I B could be obtained using the optimal modification conditions.

作者: YANG Bo JI Yubin

作者单位: School of pharmacy,Harbin University of Commerce,Harbin,150076,China Research center on life science Engineering research center on natural anticancer drugs of ministry of education,Harbin,150076,China

会议类型: 国际会议

会议名称: 2011 International Conference on Environmental Biotechnology and Materials Engineering(2011年环境生物技术与材料工程国际会议)

会议地点: 哈尔滨

会议语种:英文

页码: 2050-2054

在线出版日期: 2011-03-26（万方平台首次上网日期，不代表论文的发表时间）