The progress in relationship between CCAAT/enhancer binding proteins (C/EBPs) family and leukemia

摘要：

CCAAT/enhancer binding proteins (C/EBPs) comprise a family of transcription factors that are critical for normal cellular differentiation and function in a variety of tissues. They are not only involved in normal processes of physiological metabolism but also are related to the occurrence and development of many kinds of disorders. C/EBPs have multiple modes in which they act as activators or inhibitors in regulating transcription. These factors, particularly C/EBPα and C/EBPβ, play an important role in normal myelopoiesis. New therapeutics that can stimulate C/EBP activity or mimic their dual effects should extend the reach of differentiation therapy in leukemia.

作者: Enyu Su Houqiao Bai Guosheng Jiang

作者单位: Key Laboratory for Modern Medicine and Technology of Shandong Province, Department of Hemoto/oncology,Institute of Basic Medicine, Shandong Academy of Medical Sciences, Jinan, Shandong, China

会议类型: 国际会议

会议名称: The 4th International Conference on Bioinformatics and Biomedical Engineering(第四届IEEE生物信息与生物医学工程国际会议 iCBBE 2010)

会议地点: 成都

会议语种:英文

页码: 1-4

在线出版日期: 2010-06-18（万方平台首次上网日期，不代表论文的发表时间）