PROTEIN INTERACTION NETWORK AS A SYSTEM OF LINEAR EQUATIONS

摘要：

Research in Protein Interactions has revealed that these interactions can be considered in the form of a network and that there exists proteins with various degrees of connectivity in the network. In this paper a set of proteins sequences are treated as a system of linear equations to see whether there exist any relation between the degree of connectivity and the amino acid frequencies of protein sequences. The application of this method on a set of functional proteins revealed that there exists such a relation. Moreover this method paves a way to identify highly connected (hub) proteins from its sequence information.

作者: T.Mahalakshmi Saritha Namboodiri Achuthsankar S Nair

作者单位: University of Kerala Sree Narayana Institute of Technology Vadakevilla, Ayathil, Kollam, Kerala, Ind University of Kerala Centre for Bioinformatics, Kariavattom Thiruvananthapuram, Kerala, India 695581

会议类型: 国际会议

会议名称: The 4th International Conference on Bioinformatics and Biomedical Engineering(第四届IEEE生物信息与生物医学工程国际会议 iCBBE 2010)

会议地点: 成都

会议语种:英文

页码: 1-4

在线出版日期: 2010-06-18（万方平台首次上网日期，不代表论文的发表时间）