Analysis of Synonymous Codon Usage in the Capsid Gene UL38 of Duck Enteritis Virus

摘要：

In the study, we calculated the codon usage bias in the newly identified UL38 gene of Duck Enteritis Virus (DEV) and performed a correlation analysis of codon bias of DEV UL38 gene and its host animal.There was a strong bias in the DEV UL38 gene towards the synonymous codons with A and T at the third codon position. The amino acids codon usage bias in the DEV UL38 gene was compared with other 15 reference herpesviruses, and the cluster analysis suggested that UL38 genes type and function also contributed to the codon usage of it. In addition, there were 42 rare condons in the ORF of the DEV UL38,and 24 codons showing distinct usage differences between DEV and E. coli,12 codons between DEV and Homo sapiens, 25 codons between DEV and yeast.

作者: JunXiang Qihui Luo Hengmin Cui Yi Zhou Yin Wang Zhiwen Xu Zhengli Chen Xiaoyue Chen Xiaoyu Wang Anchun Cheng Xiaoyue Chen Anchun Cheng Mingshu Wang Shunchuan Zhang HuaChang Anchun Cheng Mingshu Wang Dekang Zhu Renyong Jia

作者单位: Avian Diseases Research Center College of Veterinary Medicine of Sichuan Agricultural University Yaa Key Laboratory of Animal Diseases and Human Health of Sichuan Province Yaan, Sichuan, 625014,China Epizootic Diseases Institute of Sichuan Agricultural University Ya’an, Sichuan, 625014, China

会议类型: 国际会议

会议名称: The 4th International Conference on Bioinformatics and Biomedical Engineering(第四届IEEE生物信息与生物医学工程国际会议 iCBBE 2010)

会议地点: 成都

会议语种:英文

页码: 1-8

在线出版日期: 2010-06-18（万方平台首次上网日期，不代表论文的发表时间）