Carbon Nanopowder Binds with DNA and May Induce DNA Aggregation

摘要：

The interaction between nanomaterials and genomes is getting more and more attention. Such studies are getting involved into several fields: environment safety, food safety, nanobiotechnology and drug development. Direct interaction between nanoparticles and DNA in vitro has been reported in several studies, but data for in vivo binding between genomic DNA and nanoparticles are rare. In this study, we presented that carbon nanopowder (CNP) is able to bind with DNA both in vitro and in vivo. Interestingly, CNP binds to DNA with a relatively high density and may induce DNA aggregation.

作者: Changlu Guo Qingdai Liu Qiaoli Ji Hongjie An Zhizhou Zhang Yadong Wang

作者单位: Research Center of Bioinformation Technology,School of Computer Science and Technology, Harbin Insti Bio-X center, College of Food Engineering and Biotechnology, Tianjin University of Science and Techn Research Center of Bioinformation Technology,School of Computer Science and Technology, Harbin Insti

会议类型: 国际会议

会议名称: The 4th International Conference on Bioinformatics and Biomedical Engineering(第四届IEEE生物信息与生物医学工程国际会议 iCBBE 2010)

会议地点: 成都

会议语种:英文

页码: 1-3

在线出版日期: 2010-06-18（万方平台首次上网日期，不代表论文的发表时间）