Isolation of one S. cerevisiae BY-14 mutant BL-23 with high-yield production of glutathione by Ion implantation

摘要：

In order to obtain a higher glutathione (GSH)production, the original strain of S. cerevisiae BY-14 was mutatedwith N+implantation (10 keV, 60×10 14 ions/cm 2) , and anethionine-resistant mutant BL-23 was obtained. The mutantshowed GSH production increased from 58.79 mg/l to 113.46mg/l,and content increased from 14.17 mg/g dry cell weight to 20.86mg/g dry cell weight. The mutant BL-23 is stable in genetic. Itshigher glutathione producing ability could be inherited after tentimes subcultures.

作者: Xuewu Guo Liping Shi Hongjiang Yang Dongguang Xiao

作者单位: Key Laboratory of Industrial Microbiology, Ministry of Education, Tianjin Industrial Microbiology Key Lab, College of Biotechnology, Tianjin University of Science and Technology, 1038 Dagunan Road, Tianjin 300222, P.R.China

会议类型: 国际会议

会议名称: The 4th International Conference on Bioinformatics and Biomedical Engineering(第四届IEEE生物信息与生物医学工程国际会议 iCBBE 2010)

会议地点: 成都

会议语种:英文

页码: 1-2

在线出版日期: 2010-06-18（万方平台首次上网日期，不代表论文的发表时间）