Multipotential Capacity of Human Adipose-derived Mesenchymal Stem Cells
Adipose tissue is derived from the embryonicmesenchyme and can be isolated easily. The purpose of this studywas to investigate the multipotent ability of adipose-derivedmesenchymal stem cells and to investigate the molecularcharacterization of adipose-derived mesenchymal stem cellsduring chondrogenic differentiation in vitro. Our results showedthat adipose-derived mesenchymal stem cells have the ability todifferentiate into adipogenic, osteogenic, and chondrogenic cellswith adipogenic, osteogenic, and chondrogenic medium in vitro.The expression of chondrogenic related molecules were detectedby RT-PCR analysis during chondrogenic differentiation. Thesestudies demonstrate that human adipose-derived mesenchymalstem cells have the multipotentiality and adipose tissue mayrepresent a novel approach to form tissue engineering cartilageto heal the damage cartilage.
Bao-Feng Guo Ling Zhang Wei-Tian Yin Kun Ji Zhuang Wei
Department of Surgery/ Prostate Diseases Prevention and Treatment Research Centre China-Japan Union Hospital, Norman Bethune Medical School, Jilin University Changchun, China
国际会议
成都
英文
1-3
2010-06-18（万方平台首次上网日期，不代表论文的发表时间）